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Decreases Nuropeptide Levels
Super CitriMax® Shown to Reduce Levels of Neuropeptide Y In Vitro
Super CitriMax® is a novel potassium/calcium salt of hydroxycitric acid (HCA) derived from Garcinia cambogia.
HCA has been reported to reduce appetite and decrease body weight both in animals and humans.
Super CitriMax® was previously shown in isolated brain tissue to increase the release of serotonin, a brain chemical that helps regulate appetite, sleep and mood.
This experiment examined the effect of Super CitriMax® on the release of neuropeptide Y, a nervous system transmitter shown to stimulate food intake.
Tissue samples from the hypothalamus and cortex of rat brains were pre-treated with varying amounts of Super CitriMax®, then chemically provoked to release neuropeptide Y.
Super CitriMax® significantly reduced neuropeptide Y levels in the hypothalamus, an area of the brain involved in controlling hunger.
The results suggest that Super CitriMax® may act to reduce food intake, in part, by reducing neuropeptide Y levels.
In a study presented at the Experimental Biology Meeting (2005), researchers showed that a key ingredient in Diab-X® "may act to reduce food intake, in part, by reducing neuropeptide Y levels."