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Decreases Nuropeptide Levels

Super CitriMax® Shown to Reduce Levels of Neuropeptide Y In Vitro

Super CitriMax® is a novel potassium/calcium salt of hydroxycitric acid (HCA) derived from Garcinia cambogia.

HCA has been reported to reduce appetite and decrease body weight both in animals and humans.

Super CitriMax® was previously shown in isolated brain tissue to increase the release of serotonin, a brain chemical that helps regulate appetite, sleep and mood.

This experiment examined the effect of Super CitriMax® on the release of neuropeptide Y, a nervous system transmitter shown to stimulate food intake.

Tissue samples from the hypothalamus and cortex of rat brains were pre-treated with varying amounts of Super CitriMax®, then chemically provoked to release neuropeptide Y.

Super CitriMax® significantly reduced neuropeptide Y levels in the hypothalamus, an area of the brain involved in controlling hunger.

The results suggest that Super CitriMax® may act to reduce food intake, in part, by reducing neuropeptide Y levels.